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Old 12-08-2006, 09:34 PM   #11 (permalink)
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I still think people have the right to state they are offended.

Sadly for Norfolk folks, people will be dubbing it deliverance central now and playing banjos when they visit.
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Old 12-08-2006, 11:30 PM   #12 (permalink)
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Quote:
Originally Posted by Aardvark
Actually I was born just outside Coventry. The city is one of the most multi-racial in the UK and inbreeding is only inbreeding in that everyone is a human being. I live in Carterton the garrison town for RAF Brize Norton - we have one of the most fluid populations in the UK. One year 30% of the electoral roll in one of the wards full of married quarters changed between annual elections. There are only a handful of locals since the settlement is only just over 100 years old and only achieved town status in the last 30 years.

My ancestry is very mixed. Gilmans from Ireland (originally England in the 16th century), Wessons from Leicestershire, Highams from Manchester, Hills from Devon, Windsors from Binley near Coventry, Tidmans from Foleshill near Coventry, Mac Dougalls and Greaves from Scotland. I married a Holland from Yorkshire, and she had Scots, Irish and Geordie forebears. I suspect I'm not very inbred at all, although some of my ancestors might have been.

The point is that the good doctor was using technically correct medical terminology to highlight a possible cause of increased propensity to diabetes. What is wrong with someone using language correctly. Surely UKIP is not arguing for a dumbing down of the English language because Sun readers only know 600 of the 100,000 or so English words. I get really annoyed when people call me posh or a snob because I choose to use technically correct words in my speech. It is the inverted snobbery of those who can't be bothered to read a dictionary or thesaurus, something I do regularly if I am not sure of a word or someone has used it in an unusual sense or even when my teenage daughter asks what certain words mean. People who read this forum regularly know that I am critical of people who argue without the use of punctuation, proper sentence construction or with spelling mistakes that cannot be attributed to the occasional typo, something we are all guilty of.

The furore, whipped up by the local press no doubt, is artificial. Norfolk does have a more stable population than much of England because of the lack of industrialisation. People, until the last 20 or 30 years, were more likely to migrate outwards to big cities than inwards in search of non-existent jobs. This meant that large numbers of small communities had no fresh blood and the people who remained were therefore 'inbred' in the technical sense. This happened elsewhere in the British Isles.

It is only an insult to people to call them inbred when it is meant to indicate a mental slowness. The people who use 'inbred' as an insult probably also call people 'spastics'. The doctor was not setting out to insult people therefore he should not apologise; he was trying to make a reasoned medical statement. He didn't suggest that the whole of Norfolk was inbred; the diabetes figures are in the hundreds. It was that group of people he thought had a problem. The press are to blame for misinterpreting and misquoting.

The point is that inbreeding leads to an increase in certain medical conditions. If people do not acknowledge the relatively good science of such a statement then illnesses will not be dealt with. I don't understand the problem here. In this country there are inbred people. There appear to be a disproportionate number in Norfolk. So what? There are more red headed Celts. We might not want to eliminate red headed people, but we might want a cure for diabetes.

If you were a GP and someone turned up with a hereditary illness would you tell them the truth or, because of political correctness, would you lie? If you would lie, and some posters imply that telling the truth is somehow wrong, then you would not have been able to eliminate Huntingdon's Chorea from the population. If your patient had an illness that was linked to inbreeding would you lie or tell the truth? The patient could then decide to marry someone outside of a close circle to reduce risk. That seems sensible to me.

My Celtic grandfather died of the now curable illness of pylo nephritis, he may also have had anomalous kidneys. My brother has anomalous kidneys and had a similar inflammation. My daughter is now cured of pylo nephritis and has anomalous kidneys. It appears to be a hereditary condition; it would be nice to prevent future generations having the same problem, but it won't happen if language puritans won't allow scientific discussion.

My mother's cousin had a rare hereditary condition. He married a woman with the same condition. They didn't realise that they were genetically as close as they were. Their son died at the age of 14 as a result of a defect caused by their intermarrying. Those of you arguing against a doctor using correct medical terminology would consign many more people to an early grave.

If you read some of the research into diabetes amongst native Americans you will note the Pima Indians, a small tribe, are over 90% susceptible to the condition. Ideally the tribe should not intermarry but should breed themselves out of existence in order to protect their children.

How on earth are we supposed to be politically incorrect if we won't allow discussion of medical conditions?

Do you all remember the fuss over paedophiles arising a few years ago? A consultant paediatrician was violently attacked.

As Hereward says she was
Quote:
Another pompous, undiplomatic scientific git!
saying that she meant something different to what was understood by the lynch mob.

If people have the benefit of a good education and can use language correctly we should be delighted. I'm the son of a Coventry car worker. I passed my 11+ and went to a grammar school. This enabled me to get a couple of degrees and be commissioned into the RAF. Surely people should be happy that the education system allowed me to progress, but no, the likes of Hereward were the same guys who used to attack the grammar school boys on the way home from school. No doubt, because I can use a few Latin aphorisms in my speech he would call me pompous and undiplomatic if I had to explain to people who didn't know what I meant even though I had only been using my professional argot.

I really do worry that people on this forum don't see the issue here.
My, my, you are full of yourself! The old phrase with the words 'wood', 'trees', 'see' and 'can't' springs to mind! You should not confuse passing written exams with 'a good education'.

I'd bore you with some of my history but, as with yours, this is not the place. (Incidentally, I just love the presumption that I did not pass MY 11+ - for what, as a standard, that was worth!)

For all your professed intelligence, you make the same mistake a housewife might make in a phone-in programme of citing her particular, single case as proof of a 'class case' (to employ legal jargon).

Neither is your 'forest' (to continue with the aphorism) of different scenarios ('If you were a GP . . ' etc) relevant.

In defending Gibson, you also discount the fact that, notwithstanding his scientific background, he is now supposed to be a politician but, if he practised his science in the same inept way he is practising his politics, one would not prudently repose much confidence in his judgement.

The fact is that Gibson made an unfortunate statement and, if he couldn't see the implications, he wasn't as smart ('wise' I guess would be a more orthodox word) as he thought he was. In any event, you are defending the indefensible, quite simply because he has realised that he erred, and he has apologised.

Effective communication is much more than the slavish adherence to particular words having particular meanings, as you have amply demonstrated in your prolix posting. I write as someone keen to be as clear and accurate as anyone.

I suppose you did your stint at Cranners, and came out with a superiority complex. The sad thing is that one does not need to be superior to suffer from that condition!
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Old 12-08-2006, 11:40 PM   #13 (permalink)
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My biggest issue is he has no real scientific proof to say they are inbred. Being called inbred isn't a nice thing, if it isn't true.

The people of Norfolk have every right to be annoyed.
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Old 13-08-2006, 12:27 AM   #14 (permalink)
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If the guy said "the people of Norfolk" are all inbred then they would, if it were not true, have grounds for complaint. The point was about propensity for a certain medical condition.

Hereward, I didn't say that you hadn't passed your 11+; I said that I had. In any event, my point was that I was able to escape, for a few years, the life of factory work that so many of my peer group entered into on leaving school.

I continue to have an excellent education in the university of life; it's not all about paper qualifications, although those help. Not all the exams I passed were written; I passed a large number of flying sorties in order to get 2000 hours as a navigator. I also passed a large number of leadership training exercises, that you also seem to pooh pooh with your insult to those of us who graduated from the Royal Air Force College Cranwell. My superiority complex comes from being elected to 2 council seats, something your party has yet to achieve!!! :roll:

I cite cases from both my own experience and from papers I have read. I really am not a Pima Indian, nor am I Afro-Carribean although I might have some Jewish blood. I talked about my origins because Matt hinted that I might be inbred; I'm not, but my family still carries certain genetic markers which is normal.

You talk of Gibson being a politician as if that meant he shouldn't speak his mind. Bob Marshall-Andrews is a politician, but Parliament would be a less interesting place if he lost his seat. Politicians are not supposed to be endowed with tact, but with an ability to speak honestly. You should have heard some of the things I said on the hustings at the last GE. I certainly confused Cameron and his ilk with straight talking on a lot of subjects.

The fact that, in your opinion, Gibson does not perform well as a politician doesn't mean that he isn't a good doctor. That is a non sequitur. Tony Blair was apparently a very average junior barrister, yet he is, in the eyes of some, a very successful politician having won 3 elections in a row - something, Hereward, I might suggest that nobody on this forum is ever likely to achieve, not even me!!! :wink:

Not everything that is said by politicians is comfortable. Tony Benn, Tam Dalyell, Dennis Skinner, Enoch Powell, Ian Paisley, Margaret Thatcher, Shirley Williams, Anne Widdecombe, to name a few, speak uncomfortable truths as seen from their own positions. None of them is called on to apologise for the hurt they might have caused by what they say and none of them would ever apologise for stating their valid opinions openly. Dr Gibson spoke the truth, as he saw it, concerning a few hundred people with Type 1 diabetes. He indicated that he thought that it was caused by inbreeding. He didn't use inbred as a pejorative term; he used it in a scientific context. Do you want politicians to speak slowly and use short words so that everyone can understand what they say?

There is nothing wrong with being inbred. The people who have taken offence see being inbred as socially unacceptable because they have hangovers from the list of relationships defined as not acceptable in the Book of Common Prayer. It is a problem, but it is not the fault of the child who is inbred, rather the parents are to blame. It is normal in some societies, but people need to be aware of the risks caused by marrying too close. That I think was the point that was being made.

Hereward, you are angry with me because I highlighted the rude comment you made. You don't seem to like people who are formally educated and your attack on the 11+ suggests that you either did not take it or did not pass it. I make no apologies for being prolix. I enjoy the sound of my own keyboard.

Back to hypothesis, would you, as a politician, state the truth, even though it is hurtful, or would you lie to keep the proles happy? Is it the position of the EDP that telling unhurtful truths is not politically acceptable? Did you really intend to type everything in bold so that your opinion stands out from others? Perhaps you're as up yourself as I am (I know what I mean). :twisted:
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Old 13-08-2006, 07:40 AM   #15 (permalink)
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Ian Gibson is my constituency MP. He is greatly respected as he speaks his mind (against ID cards for example), and has not sold out his principles for office. One of the things he is campaigning about is to find out more information about the experiment in the 1960s where chemicals were dropped on Norwich to see what the effect on health would be, it appears that the incidence of certain cancers has increased.

He has apologised for using the term "inbreeding" as he realises that this scientific term sounds insulting to the lay person.

None of the above have stopped, or will stop, our branch putting up a UKIP candidate against him.
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Old 13-08-2006, 12:47 PM   #16 (permalink)
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Quote:
Originally Posted by Aardvark
If the guy said "the people of Norfolk" are all inbred then they would, if it were not true, have grounds for complaint. The point was about propensity for a certain medical condition. [THE point is that he made a statement which was likely to be regarded as offensive,]

Hereward, I didn't say that you hadn't passed your 11+; I said that I had. [In the following sentence, you said: " . . the likes of Hereward were the same guys who used to attack the grammar school boys on the way home from school." Would you have me believe that these "same guys" had also been to grammar school?]
In any event, my point was that I was able to escape, for a few years, the life of factory work that so many of my peer group entered into on leaving school.[Good for you. Success in passing the 11+ was affected by a number of factors, which included: (1) the number of grammar school places available relative to particular 'school populations' and (2) the general standard of education amongst those competing for particular places. For these reasons alone, the 11+ could not be regarded as setting a nationwide standard.]


I continue to have an excellent education in the university of life; it's not all about paper qualifications, although those help. Not all the exams I passed were written; I passed a large number of flying sorties in order to get 2000 hours as a navigator. I also passed a large number of leadership training exercises, that you also seem to pooh pooh with your insult to those of us who graduated from the Royal Air Force College Cranwell.[I poo, poo your superiority complex. It would not only be a prejudice, but silly, to tar every Cranwell 'graduate' alike.]
My superiority complex comes from being elected to 2 council seats, something your party has yet to achieve!!! [HMmm! Theories of pyschiatry might suggest something different. Even so, congratulations on your success in getting elected (I am not being ironic here), but I do not regard the EDP in any way diminished by your comments which, in some circumstances, I might feel tempted to describe as 'snide', but I have the impression that you are already on the defensive, so I will not indulge myself. It is my opinion that UKIP has some good quality members, as evidenced by some of the postings here. Unfortunately, as with all parties, it has its quota of the 'not so good'.]
:roll:

I cite cases from both my own experience and from papers I have read. I really am not a Pima Indian, nor am I Afro-Carribean although I might have some Jewish blood. I talked about my origins because Matt hinted that I might be inbred; I'm not, but my family still carries certain genetic markers which is normal. [You seem preternaturally sensitive and defensive.]


You talk of Gibson being a politician as if that meant he shouldn't speak his mind. [No, that is your interpretation, totally unsupported by anything I wrote.]
Bob Marshall-Andrews is a politician, but Parliament would be a less interesting place if he lost his seat. Politicians are not supposed to be endowed with tact, but with an ability to speak honestly.[There is a difference between being honest and being offensive.]
You should have heard some of the things I said on the hustings at the last GE. I certainly confused Cameron and his ilk with straight talking on a lot of subjects.[All this is aside from Gibson's indicretion here.]


The fact that, in your opinion, Gibson does not perform well as a politician doesn't mean that he isn't a good doctor. [He is not paid to be a doctor. His current occupation is MP.]
That is a non sequitur. [I fear the beam is in your eye.]
Tony Blair was apparently a very average junior barrister, yet he is, in the eyes of some, a very successful politician having won 3 elections in a row - something, Hereward, I might suggest that nobody on this forum is ever likely to achieve, not even me!!! :wink: [Not relevant. Please concentrate, instead of shifting ground. Blair is now a politician. Indeed, he has practised politics far longer than he ever practised as a barrister professionally ie in the Courts for fees.]


Not everything that is said by politicians is comfortable. Tony Benn, Tam Dalyell, Dennis Skinner, Enoch Powell, Ian Paisley, Margaret Thatcher, Shirley Williams, Anne Widdecombe, to name a few, speak uncomfortable truths as seen from their own positions. None of them is called on to apologise for the hurt they might have caused by what they say and none of them would ever apologise for stating their valid opinions openly. Dr Gibson spoke the truth, as he saw it, concerning a few hundred people with Type 1 diabetes. He indicated that he thought that it was caused by inbreeding. He didn't use inbred as a pejorative term; he used it in a scientific context. Do you want politicians to speak slowly and use short words so that everyone can understand what they say? [Irrelevant verbiage. You have shifted ground again.]


There is nothing wrong with being inbred. The people who have taken offence see being inbred as socially unacceptable because they have hangovers from the list of relationships defined as not acceptable in the Book of Common Prayer. It is a problem, but it is not the fault of the child who is inbred, rather the parents are to blame. It is normal in some societies, but people need to be aware of the risks caused by marrying too close. That I think was the point that was being made.[Again, not relevant. You must learn to concentrate.]


Hereward, you are angry with me because I highlighted the rude comment you made.[That is your interpretation. I could be equally subjective, and attribute particular emotions to your comments. Again, you do not seem to be aware of how presumptious you can be.]
You don't seem to like people who are formally educated and your attack on the 11+ suggests that you either did not take it or did not pass it. [I did take it and, for what it was worth, I passed despite having a severe pain from an ear abcess during the second part, which burst shortly thereafter. Boring, isn't it.]
I make no apologies for being prolix. I enjoy the sound of my own keyboard. [It's all very well for you to indulge yourself when a result is to obfuscate the issue.]


Back to hypothesis, would you, as a politician, state the truth, even though it is hurtful, or would you lie to keep the proles happy?[What useful and constructive purpose has been served by Dr Gibson's outburst?]
Is it the position of the EDP that telling unhurtful truths is not politically acceptable? [No, but this is beside the point.]
Did you really intend to type everything in bold so that your opinion stands out from others? Perhaps you're as up yourself as I am (I know what I mean). :twisted:[You are free to draw your own conclusion and, thus far, to state it however undesirable that might be.]
Perhaps my colour perception is not as good as it was, but posting in bold or both bold and colour seems to make it easier to distinguish between who is saying what.

I do not always do it. You may care to draw an unnecessary conclusion from that - inconsistency perhaps? It's the artist in me!
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Old 13-08-2006, 02:07 PM   #17 (permalink)
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How can we all know which statements we make are likely to be found offensive? Dr Gibson didn't expect to cause offence. He has apologised if he did cause offence, but I suspect that most people in Norfolk didn't take umbrage. Why on earth would they?

Dr Gibson made a statement in good faith. He is indeed paid as a MP, but he is still a doctor of science (he is described elsewhere as a former science lecturer). His expertise should be recognised - some of the doctors of medicine in Parliament continue to practice or maintain currency in their respective specialisations in order to be ready to return to their profession after being a politician (Drs Taylor and Harris definitely practice medicine). Many of the lawyers in Parliament also continue to practice; they are both MPs and lawyers. The journalists also continue in their professions. Let's face it, being a MP is a part time job after all!

I accept I implied you might not have passed your 11+ for which I apologise, but you still made a few throwaway comments which could be interpreted as snide and being prejudiced against people with professional or paper qualifications. The 11+ was a national standard, but you are correct in that some towns and cities had limited places available to pupils. For historic reasons Coventry had less places for girls than boys.

I honestly don't have a superiority complex; I just get frustrated at a lot of the pointless name calling on this forum together with the willingness of some people to rely heavily on very suspect links to weird and wonderful websites which lack objectivity and grind axes as if we all had forests to chop down! I have learnt a lot being on this forum and have been directed to some fascinating links. I have even changed my views on the basis of some of the information that I have become privy to. We lower ourselves, however, when we take the debate down to name calling such as your..
Quote:
Another pompous, undiplomatic scientific git!
I'm sure I've gone down this route on occasion, but I try to be more subtle about it.

I'm not on the defensive. I'm not ranting in red and black to draw attention to my posts. I'm actually attacking in a very subtle and ironic way.

I haven't used irrelevant material or shifted ground. I wasn't only responding to you, but other posters as well. You put me in a no win situation by having a go at me for being like the telephone caller who only draws on her own experience and likewise having a go at me for raising broader issues to highlight my points in this debate. I think it is you who is on the defensive and shifting ground, or do you still believe that your quote above is a valid contribution to this debate?

I don't think detailed argument obfuscates issues, but instead serves to expand the debate in a meaningful way. I think that Dr Gibson's comment (not outburst) was designed to expand the discussion as to why more people in Norfolk are susceptible to Type 1 diabetes than might ordinarily be expected. The comment has served a purpose since outside the sensationalist media and Internet fora such as this there will be clinical experts who will either support or oppose the comments and put their discussions into learned medical journals.

Here is a clue to where Dr Gibson might be coming from:
Quote:
Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping.

Lyons PA, Armitage N, Argentina F, Denny P, Hill NJ, Lord CJ, Wilusz MB, Peterson LB, Wicker LS, Todd JA.

Department of Medical Genetics, Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, University of Cambridge, UK. paul.lyons@cimr.cam.ac.uk

Type 1 diabetes in the nonobese diabetic (NOD) mouse arises as a consequence of T cell-mediated destruction of the insulin-producing beta cells of the pancreas. Although little is known of the events that initiate and subsequently drive beta-cell destruction it is clear that the entire process is under complex genetic control. At present 19 loci have been mapped that influence the development of diabetes either at the level of initiation of insulitis or at the level of progression from insulitis to overt diabetes, or both. Previously, we have mapped one of these loci, Idd3, to a 0.35-cM interval on proximal mouse chromosome 3. In the present study we have narrowed the map position of this locus to an interval of 0.15 cM by a combination of novel congenic strains and an ancestral haplotype analysis approach. We have constructed a physical contig in bacterial artificial chromosome (BAC) clones across the minimal interval. Restriction mapping of the BAC contig placed the maximum size of the Idd3 interval at 780 kb between the markers D3Nds36 and D3Nds76. To refine further the Idd3 interval we developed a series of novel single nucleotide polymorphisms (SNPs) and carried out haplotype analysis on DNA from mouse strains known to carry either Idd3 susceptibility or protective alleles. This haplotype analysis identified a 145-kb segment of ancestral DNA between the microsatellite marker D3Nds6 and the SNP 81.3. One haplotype of this ancestral segment of DNA is found in mouse strains carrying an Idd3 susceptibility allele and another is found in mouse strains carrying an Idd3 protective allelle. Within the 780-kb congenically defined interval this 145-kb segment represents the most likely location for Idd3. The Il2 gene, which encodes the cytokine interleukin 2 (IL2), maps to this interval and is a strong candidate for Idd3. To investigate whether sequence variation exists in the promoter region of the Il2 gene, which might alter its expression, we sequenced the promoter region of the Il2 gene from mouse strains carrying either an Idd3 susceptibility or resistance allele. Two sequence variants were identified, neither of which fell in known regulatory elements within the Il2 promoter. In agreement with this observation steady-state Il2 mRNA levels showed no variation between susceptible and resistant mouse strains. These data suggest that the profound protection from diabetes seen in congenic mice carrying an Idd3 protective allele is unlikely to be due to differences in the level of expression of the Il2 gene. Instead, all of the current data support our hypothesis that Idd3 corresponds to amino acid variation at the amino terminus of Il2.
Kloting and Kloting in their paper, " Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat." argue that, " Spontaneous diabetes in B(io)B(reeding) rats is complex, polygenic, and recessively inherited. ".

See also:
http://www.uchsc.edu/misc/diabetes/oxch3.html

In fact if you Google "Type 1 diabetes"+DNA+inbreeding you will get 28000 links.

You see Dr Gibson is only potentially talking about facts established from medical research. I have now read a whole lot of this material and have learnt a lot because of this discussion. I've also got to read a good medical dictionary to find out what I have learnt!!!! :wink:

Scientific debate should not be censored by reference to sensationalist journalism. That is what I believe is the result of the argument that someone should apologise for adding to scientific debate.
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Old 13-08-2006, 02:15 PM   #18 (permalink)
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For balance: http://noorderlicht.vpro.nl/attachme...ia%202004b.pdf
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Old 13-08-2006, 02:39 PM   #19 (permalink)
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For historic reasons Coventry had less places for girls than boys.
Tsk! tsk! For historic reasons Coventry had fewer places for girls than boys - and you a grammar school boy! :wink:
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Old 13-08-2006, 05:58 PM   #20 (permalink)
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...and me in mid-rant! :wink:
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